Position: Principal Scientist – Team Leader Assay Development
Location: Cambridge
Salary: Competitive

A growing Biotechnology company are currently looking to recruit a Principal Scientist to lead their assay development team.

The Role

As the Principal Scientist within Assay Development you’ll be responsible for designing, developing and optimising in vitro biological assays and establishment of Standard operating procedures and protocols, and will be expected to be an ambassador for quality in analytical procedures.

Key Responsibilities:
• To lead a team performing experiments involving the development of controlled methods for pre-clinical analytics (e.g. PK assays), drug candidate characterisation and clinical release assays
• To lead assay development projects involving cross-functional teams, independently design and execute project goals, plans and milestones in alignment with established programme strategy
• To contribute a broad technical skill set as well as understanding of rigorous approach to assay development and maintenance, ensuring robust methods are available to span drug discovery and development processes
• To lead outsourcing activities covering bioanalytical assays as well as release bioassays and reagent generation
• Ensure the team performs experiments and data management activities in a robust manner and produces quality data to inform decision making on projects
• Carry out and support on-going analyses of data generated, to identify issues and implement necessary changes.
• Implement best practice and keep up to date with regulatory guidelines with a view to transferring methods into a regulated environment to be used under GLP and GMP regulations
• Identify critical project-related issues and successfully implement plans to overcome them to ensure the achievement of goals/milestones.
• Read scientific and technical literature and keep up with the new trends and techniques related to role

You

Ideally you’ll have a PhD or equivalent industry experience where you’ve gained considerable industry experience with a focus on assay development for a regulated environment and extensive experience in structured assay design, record keeping and understanding of factors affecting assay robustness and levels of data quality.
Solid understanding of statistics applied to bioassays and proficiency in PK Assays, cell biology, in vitro Immuno Assays, Flow Cytometry, In Vitro Cell activation assays, ADCC, CDC, ADCP, Cell Culture, Analysis and purification of primary murine and human immune cells and immunological phenotyping.
You’ll have proven experience in a small team designing and optimising biological and immunological assays, extensive experience in structured assay design and a good track record of research outputs.

Company

A leading Biotechnology Company who have gone through significant growth and are focused on the development of Bispecific Antibodies for the treatment of serious diseases including Immune Oncology.

Salary and Benefits

Salaries are very competitive and discussed during the interview process with benefits including Pension Scheme, Life Assurance and Private Medical Insurance. This company has gone through significant growth the past 12 months and they offer great career progression opportunities.

Apply Now

To be considered for the Principal Scientist in Assay Development and have the chance to work for a cutting edge company please send your CV to Natasha Robbins at Fuse Science Recruitment via the apply now button